Effects of COVID-19 on Multiple Sclerosis Relapse: A Comprehensive Review

Multiple Sclerosis is a chronic inflammatory disease. It characterized by demyelinating lesions throughout the central nervous system. Patients suffering from multiple sclerosis constitute vulnerable population to coronavirus disease-2019. This review focuses on effects of disease-2019 relapse and symptom exacerbation in patients their treatment. highlights how blood-brain barrier may be compromised severe acute respiratory syndrome 2, allowing mediators lymphocytes infiltrate increase risk patients. Also, who did not have prior history sclerosis, has been found impact onset pathogenesis. However, more comprehensive research required fully understand interplay between